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Treatment of Cryptococcal Meningitis Associated with the Acquired Immunodeficiency Syndrome NEJM 337:15-21, VanDerHorst,C.M.,et al, 1997 See this aricle in Pubmed Article Abstract For the initial treatment of AIDS-associated cryptococcal meningitis,the use of higher-dose amphotericin B plus flucytosine is associated with an increased rate of cerebrospinal fluid sterilization and decreased mortality at two weeks,as compared with regimens used in previous studies. Although consolidation therapy with fluconzole is associated with a higher rate of cerebrospinal fluid sterilization,itraconazole may be a suitable alternative for patients unable to take fluconazole.

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